Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL8447860 | 0.91 | KCNH2 (0.31) | — | |
| Iodide SCHEMBL8454502 | 0.83 | — | — | |
| SCHEMBL8728387 | 0.78 | — | — | |
| Iodide SCHEMBL8451881 | 0.77 | KCNH2 (0.32) | HIF1A | |
| Iodide SCHEMBL13280558 | 0.75 | HIF1A (0.48) | HIF1A | |
| SCHEMBL7758069 | 0.74 | — | — | |
| Iodide SCHEMBL8189357 | 0.74 | HIF1A (0.38) | HIF1A | |
| Iodide SCHEMBL7042578 | 0.74 | HIF1A (0.38) | HIF1A | |
| Iodide SCHEMBL8182049 | 0.74 | HIF1A (0.40) | HIF1A | |
| Iodide SCHEMBL8182047 | 0.74 | HIF1A (0.40) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004478-A | LIQUID CRYSTAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0732335-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |