Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453479 | 1.00 | RARB (0.46) | RARBRARARARGHSD11B1HRH3 | |
| SCHEMBL8455944 | 0.99 | RARB (0.47) | RARBRARARARGHSD11B1HRH3 | |
| SCHEMBL8453698 | 0.99 | RARB (0.47) | RARBRARARARGHSD11B1HRH3 | |
| SCHEMBL8453689 | 0.99 | RARB (0.47) | RARBRARARARGHSD11B1HRH3 | |
| SCHEMBL8455954 | 0.99 | RARB (0.47) | RARBRARARARGHSD11B1HRH3 | |
| SCHEMBL8451717 | 0.97 | RARB (0.41) | RARBRARARARGHSD11B1SIGMAR1 | |
| SCHEMBL8451708 | 0.97 | RARB (0.41) | RARBRARARARGHSD11B1SIGMAR1 | |
| SCHEMBL8453769 | 0.94 | SPHK1 (0.44) | RARBRARARARGSPHK1 | |
| SCHEMBL8453764 | 0.94 | SPHK1 (0.44) | RARBRARARARGSPHK1 | |
| SCHEMBL8447439 | 0.93 | SPHK1 (0.46) | RARBRARARARGSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |