Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453510 | 1.00 | PROKR1 (0.34) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8453506 | 1.00 | PROKR1 (0.34) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8451935 | 0.91 | CYP2C9 (0.36) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8453481 | 0.91 | PROKR1 (0.34) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8453488 | 0.91 | PROKR1 (0.34) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8453484 | 0.91 | PROKR1 (0.34) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8451939 | 0.91 | CYP2C9 (0.36) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8451942 | 0.91 | CYP2C9 (0.36) | PROKR1OPRL1FPR2CCR3KCNH2 | |
| SCHEMBL8447733 | 0.89 | ESR2 (0.38) | PROKR1OPRL1FPR2ESR2 | |
| SCHEMBL8447726 | 0.89 | ESR2 (0.38) | PROKR1OPRL1FPR2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |