Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.52 |
| ▸ | RARA | P10276 | 2/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453517 | 1.00 | RARB (0.52) | RARBRARARARGHRH3HSD17B10 | |
| SCHEMBL8453523 | 1.00 | RARB (0.52) | RARBRARARARGHRH3HSD17B10 | |
| SCHEMBL8453536 | 1.00 | RARB (0.52) | RARBRARARARGHRH3HSD17B10 | |
| SCHEMBL8448529 | 0.99 | RARB (0.50) | RARBRARARARGHRH3HSD17B10 | |
| SCHEMBL8448525 | 0.99 | RARB (0.50) | RARBRARARARGHRH3HSD17B10 | |
| SCHEMBL8448252 | 0.95 | RARB (0.45) | RARBRARARARGHRH3MAPT | |
| SCHEMBL8448249 | 0.95 | RARB (0.45) | RARBRARARARGHRH3MAPT | |
| SCHEMBL8764719 | 0.93 | SPHK1 (0.50) | RARBRARARARGSPHK1 | |
| SCHEMBL8448471 | 0.93 | SPHK1 (0.50) | RARBRARARARGSPHK1 | |
| SCHEMBL8448477 | 0.93 | SPHK1 (0.50) | RARBRARARARGSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |