SCHEMBL8454582

SCHEMBL8454582

[CH2]CCCCCCCCCNC(=O)C(CC)CCCC

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.60
CA2 P00918 6/20 0.54
CA1 P00915 4/20 0.54
DPP7 Q9UHL4 2/20 0.50
TSHR P16473 2/20 0.48
RRM1 P23921 1/20 0.46
MAPK1 P28482 1/20 0.46
GNAI3 P08754 1/20 0.44
GNAO1 P09471 1/20 0.44
GNAI1 P63096 1/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
EPHX1 P07099 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8458547 1.00 USP2 (0.60) USP2CA2CA1DPP7TSHR
SCHEMBL22414705 0.88 USP2 (0.69) USP2CA2CA1DPP7TSHR
SCHEMBL5491789 0.86 USP2 (0.71) USP2CA2CA1DPP7TSHR
SCHEMBL11692574 0.84 USP2 (0.69) USP2CA2CA1DPP7TSHR
SCHEMBL26478805 0.83 USP2 (0.58) USP2CA2CA1DPP7TSHR
SCHEMBL9676595 0.83 USP2 (0.58) USP2CA2CA1DPP7TSHR
SCHEMBL18541163 0.83 USP2 (0.66) USP2CA2CA1DPP7TSHR
SCHEMBL8041514 0.83 USP2 (0.58) USP2CA2CA1DPP7TSHR
SCHEMBL8454571 0.82 USP2 (0.55) USP2CA2CA1DPP7TSHR
SCHEMBL16390491 0.81 USP2 (0.65) USP2CA2CA1DPP7TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691327-B1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME KAO CORP (JP) 1999-07-21 EP disclosed
US-5723497-A AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0691327-A1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME Kao Corporation (JP) 1996-01-10 EP disclosed