Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845500 | 1.00 | HPGD (0.51) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL845457 | 0.98 | HPGD (0.55) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL845120 | 0.96 | HPGD (0.47) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL845476 | 0.95 | HPGD (0.46) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL845129 | 0.91 | F2 (0.45) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL10119592 | 0.90 | F2 (0.43) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL17474773 | 0.90 | HPGD (0.54) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL17488503 | 0.90 | HPGD (0.54) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL872291 | 0.88 | F2 (0.41) | HPGDPOLBALDH1A1F2RAB9A | |
| SCHEMBL3046784 | 0.86 | HPGD (0.51) | HPGDPOLBALDH1A1F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |