Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456053 | 1.00 | SPHK1 (0.36) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8456041 | 1.00 | SPHK1 (0.36) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8451491 | 0.99 | SPHK1 (0.38) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8452050 | 0.99 | SPHK1 (0.38) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8452053 | 0.99 | SPHK1 (0.38) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8452056 | 0.99 | SPHK1 (0.38) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8451497 | 0.99 | SPHK1 (0.38) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8451498 | 0.99 | SPHK1 (0.38) | SPHK1S1PR1SPHK2SIGMAR1CYP3A4 | |
| SCHEMBL8453694 | 0.97 | SPHK1 (0.34) | SPHK1S1PR1SPHK2SIGMAR1CYP2C9 | |
| SCHEMBL8453690 | 0.97 | SPHK1 (0.34) | SPHK1S1PR1SPHK2SIGMAR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |