SCHEMBL845749

SCHEMBL845749

C=C(C)C(=O)OCCC[Si](CCCOC(=O)C(=C)C)(CCCOC(=O)C(=C)C)OC

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.47
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537670 0.93 TSHR (0.57) TSHRTHRBTDP1POLBAPEX1
SCHEMBL14983562 0.91 TSHR (0.50) TSHRTHRBTDP1POLBAPEX1
SCHEMBL340795 0.91 TSHR (0.54) TSHRTHRBTDP1POLBAPEX1
SCHEMBL16536417 0.89 TSHR (0.60) TSHRTHRBTDP1POLBAPEX1
SCHEMBL16537755 0.87 TSHR (0.54) TSHRTHRBTDP1POLBAPEX1
SCHEMBL16537994 0.87 TSHR (0.63) TSHRTHRBTDP1POLBAPEX1
SCHEMBL16537168 0.86 TSHR (0.57) TSHRTHRBTDP1POLBAPEX1
SCHEMBL845108 0.85 TSHR (0.55) TSHRTHRBTDP1POLBAPEX1
SCHEMBL15276 0.85 TSHR (0.55) TSHRTHRBTDP1POLBAPEX1
SCHEMBL5446210 0.85 TSHR (0.55) TSHRTHRBTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256238-B2 Modified block copolymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-08-14 US claimed
CN-118574883-A Rubber formulation comprising functionalized conjugated diene polymer, natural rubber and reinforcing filler 株式会社普利司通 2024-08-30 CN disclosed
US-20220171305-A1 EXTERNAL ADDITIVE PARTICLES, TONER, AND METHOD FOR PRODUCING EXTERNAL ADDITIVE PARTICLES CANON KABUSHIKI KAISHA (JP) 2022-06-02 US disclosed
US-20220128920-A1 EXTERNAL ADDITIVE PARTICLE AND TONER CANON KABUSHIKI KAISHA (JP) 2022-04-28 US disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
US-20180022913-A1 Block Copolymer Composition, Molded Material, Resin Composition, and Molded Product ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-01-25 US disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-9416252-B2 Rubber composition for tire tread THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-08-16 US disclosed
US-6096476-A DIRECTLY IMAGEABLE RAW PLATE HAVING A HEAT INSULATING LAYER, HEAT SENSITIVE LAYER COMPRISING A LIGHT TO HEAT CONVERTING MATERIAL AND INK REPLELLENT LAYER IN THIS ORDER ON SUBSTRATE; PLATE HAS SPECIFIED ELASTIC MODULUS AND TENSILE PROPERTIES TORAY INDUSTRIES, INC. (JP) 2000-08-01 US disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed
EP-0802067-A1 DIRECT DRAWING TYPE WATERLESS PLANOGRAPHIC ORIGINAL FORM PLATE TORAY INDUSTRIES, INC. (JP) 1997-10-22 EP disclosed
US-5670257-A HYDROLYZING AND CONDENSING ORGANOSILICON COMPOUND; HEAT TREATMENT; SPACERS FOR LIQUID CRYSTAL DISPLAY; NONFRACTURING NIPPON SHOKUBAI CO., LTD. (JP) 1997-09-23 US disclosed
US-5662961-A Method for forming a protective coating film on electronic parts and devices TOKYO OHKA KOGYO CO., LTD. (JP) 1997-09-02 US disclosed
EP-0767179-A2 Method for producing a rubber composition Bridgestone Corporation (JP) 1997-04-09 EP disclosed
US-5580619-A LIQUID CRYSTAL DISPLAY NIPPON SHOKUBAI CO., LTD. (JP) 1996-12-03 US disclosed
US-5520952-A Method for forming a protective coating film on electronic parts and devices TOKYO OHKA KOGYO CO., LTD. (JP) 1996-05-28 US disclosed
US-5503932-A SPACERS FOR LIQUID CRYSTAL DISPLAYS REQUIRING UNIFORM GAP DISTANCE BETWEEN MEMBERS; RESILIENCE NIPPON SHOKUBAI CO., LTD. (JP) 1996-04-02 US disclosed
EP-0653663-A1 Organic-inorganic composite particles and production process therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-05-17 EP disclosed