Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | RARB | P10826 | 1/20 | 0.62 |
| ▸ | RARG | P13631 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458033 | 1.00 | SRD5A2 (0.69) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| Benzoic Acid SCHEMBL19875753 | 0.93 | SRD5A2 (0.59) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL8459973 | 0.88 | MAPT (0.78) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL8459972 | 0.88 | MAPT (0.78) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL36693 | 0.88 | SRD5A2 (0.87) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1017064 | 0.86 | SRD5A2 (0.83) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL592353 | 0.86 | SRD5A2 (0.83) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL3842685 | 0.86 | SRD5A2 (0.83) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL9120613 | 0.86 | SRD5A2 (0.83) | SRD5A2CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL205291 | 0.86 | SRD5A2 (0.83) | SRD5A2CA1CA2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048529-A1 | RETINOID-GLITAZONE COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |