Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769767 | 0.62 | KDM4E (0.48) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL625521 | 0.62 | KDM4E (0.48) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL235710 | 0.61 | KDM4E (0.54) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL70135 | 0.61 | KDM4E (0.54) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL30442476 | 0.61 | KDM4E (0.54) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL6913078 | 0.61 | KDM4E (0.47) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL6915834 | 0.61 | KDM4E (0.47) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL6908680 | 0.61 | KDM4E (0.47) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL6913400 | 0.61 | KDM4E (0.47) | KDM4ENOTUMMEN1KMT2ATDP1 | |
| SCHEMBL6914572 | 0.61 | KDM4E (0.47) | KDM4ENOTUMMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901485-A1 | 1,2-BENZOXATHIIN AND THIEPIN 2,2-DIOXIDE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997042185-A1 | 1,2-BENZOXATHIIN AND THIEPIN 2,2-DIOXIDE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |