Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458932 | 1.00 | TTR (0.50) | TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL8460279 | 1.00 | TTR (0.50) | TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL4454206 | 0.87 | — | — | |
| SCHEMBL3137720 | 0.71 | TTR (1.00) | TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL78595 | 0.71 | TTR (1.00) | TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL1119 | 0.71 | TTR (1.00) | TTRMEN1KMT2AALDH1A1 | |
| Dioxane SCHEMBL3631647 | 0.71 | TTR (1.00) | TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11207601 | 0.71 | TTR (1.00) | TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL6057268 | 0.71 | TTR (1.00) | TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL16041435 | 0.71 | TTR (1.00) | TTRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779888-B1 | PYRIMIDO [5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-04-28 | — | — | EP | claimed |