SCHEMBL8459174

SCHEMBL8459174

CCCCCc1cccc(C(=O)O)c1N(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.52
MCL1 Q07820 6/20 0.52
BCL2L1 Q07817 5/20 0.52
BAK1 Q16611 5/20 0.52
KAT8 Q9H7Z6 5/20 0.52
PPARA Q07869 4/20 0.52
PPARG P37231 2/20 0.52
SAE1 Q9UBE0 2/20 0.52
EP300 Q09472 2/20 0.52
KAT5 Q92993 2/20 0.52
KAT2A Q92830 1/20 0.52
KAT2B Q92831 1/20 0.52
F7 P08709 3/20 0.46
F3 P13726 3/20 0.46
MMP2 P08253 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
ECE1 P42892 1/20 0.46
SGMS1 Q86VZ5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4877389 0.98 BID (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL7996297 0.85 TDP1 (0.44) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL129586 0.84 CLCN2 (0.50) KDM4EALOX15HSD17B10
SCHEMBL29023625 0.83 SLC16A3 (0.39) BIDMCL1BCL2L1BAK1KAT8
Hydrochloric Acid SCHEMBL27971721 0.83 BID (0.45) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL27580410 0.82 TSHR (0.48) BIDMCL1BCL2L1BAK1KAT8
Trimethylammonium SCHEMBL7717887 0.81 BID (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL623528 0.80 FOLH1 (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5171335 0.80 FOLH1 (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL29902881 0.80 FOLH1 (0.59) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711801-B1 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING (US) 1999-10-06 EP disclosed
EP-0711801-A2 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING CORPORATION (US) 1996-05-15 EP disclosed
EP-0711802-A2 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING CORPORATION (US) 1996-05-15 EP disclosed
EP-0456346-B1 Silicone organic conformal coatings DOW CORNING (US) 1994-10-12 EP disclosed
US-5302627-A For polysiloxanes DOW CORNING CORPORATION (US) 1994-04-12 US disclosed
EP-0456346-A2 Silicone organic conformal coatings DOW CORNING CORPORATION (US) 1991-11-13 EP disclosed
EP-0437247-A2 UV curable silicone resin-organic mercaptan composition DOW CORNING CORPORATION (US) 1991-07-17 EP disclosed