SCHEMBL8459558

SCHEMBL8459558

CCC(CO)OC(=O)/C=C\C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 0.53
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
MAPT P10636 2/20 0.34
MAPK1 P28482 1/20 0.34
PRKCA P17252 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049907 1.00 HCAR2 (0.53) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL6049911 1.00 HCAR2 (0.53) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL6049905 0.92 HCAR2 (0.40) HCAR2MAPTMAPK1PRKCAALDH1A1
SCHEMBL5175102 0.90 HCAR2 (0.59) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL5175849 0.90 HCAR2 (0.59) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL5175099 0.90 HCAR2 (0.59) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL15570481 0.88 HCAR2 (0.56) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL4439679 0.88 HCAR2 (0.56) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL8459101 0.85 HCAR2 (0.50) HCAR2MAPTMAPK1PRKCATDP1
SCHEMBL8461078 0.84 HCAR2 (0.51) HCAR2TSHRMAPTMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130261254-A1 REACTIVE DILUENTS, METHODS OF REACTING, AND THERMOSET POLYMERS DERIVED THEREFROM SEGETIS, INC. (US) 2013-10-03 US disclosed
WO-2013148933-A1 REACTIVE DILUENTS, METHODS OF REACTING, AND THERMOSET POLYMERS DERIVED THEREFROM SEGETIS, INC. (US) 2013-10-03 WO disclosed
EP-0607900-B1 Resin composition for artificial marble, bulk molding compound and sheet molding compound using the same, and process for preparing artificial marble using the same HITACHI CHEMICAL CO LTD (JP) 1999-04-14 EP disclosed
US-5356953-A Resin composition for artificial marble, bulk molding compound and sheet molding compound using the same, and process for preparing artificial marble using the same HITACHI CHEMICAL COMPANY LIMITED (JP) 1994-10-18 US disclosed
EP-0607900-A2 Resin composition for artificial marble, bulk molding compound and sheet molding compound using the same, and process for preparing artificial marble using the same Hitachi Chemical Co., Ltd. (JP) 1994-07-27 EP disclosed