Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462184 | 0.98 | KDM4E (0.48) | KDM4EGAACYP3A4TDP1NOS3 | |
| SCHEMBL18029551 | 0.75 | KDM4E (0.55) | KDM4EGAACYP3A4TDP1NPC1 | |
| SCHEMBL9623906 | 0.75 | GAA (0.46) | KDM4EGAACYP3A4TDP1NPC1 | |
| O-Xylene SCHEMBL5617302 | 0.74 | CYP3A4 (0.71) | KDM4EGAACYP3A4TDP1CYP2A6 | |
| SCHEMBL28610467 | 0.73 | KDM4E (0.48) | KDM4EGAACYP3A4TDP1HTT | |
| SCHEMBL20903808 | 0.71 | KDM4E (0.46) | KDM4EGAACYP3A4TDP1NPC1 | |
| SCHEMBL28155942 | 0.71 | TRIM24 (0.48) | KDM4EGAACYP3A4TDP1NPC1 | |
| Potassium Chloride SCHEMBL27500141 | 0.71 | KDM4E (0.50) | KDM4EGAACYP3A4TDP1NOS3 | |
| SCHEMBL10819825 | 0.70 | KDM4E (0.60) | KDM4EGAACYP3A4TDP1NOS3 | |
| Hydrochloric Acid SCHEMBL10793333 | 0.70 | CYP3A4 (0.48) | KDM4EGAACYP3A4TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860782-B1 | Semiconducting material comprising a phosphine oxide matrix and metal salt | NOVALED GMBH (DE) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017089399-A1 | ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS | NOVALED GMBH (DE) | 2017-06-01 | — | — | WO | disclosed |
| EP-0386833-B1 | Carbonylation catalyst system | SHELL INT RESEARCH (NL) | 1999-06-16 | — | — | EP | disclosed |
| EP-0441447-B1 | Carbonylation catalyst process | SHELL INT RESEARCH (NL) | 1994-11-30 | — | — | EP | disclosed |
| EP-0441446-B1 | Carbonylation catalyst system | SHELL INT RESEARCH (NL) | 1994-05-04 | — | — | EP | disclosed |
| EP-0441445-B1 | Preparation of amides | SHELL INT RESEARCH (NL) | 1994-05-04 | — | — | EP | disclosed |
| US-5179225-A | Reaction of acetylenic or olefinic compound with carbon monoxide | SHELL OIL COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
| US-5166116-A | Coordination catalysts of phosphine, group 8 metal, protons and sulfonate | SHELL OIL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| US-5166411-A | Group 8 metal, a phosphine, a proton source and a tertiary amine | SHELL OIL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| US-5158921-A | Catalyst system which contains palladium compound and phosphine | SHELL OIL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5128475-A | PREPARATION OF AMIDES | SHELL OIL COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| US-5124300-A | Group 8 metal, aromatic phosphine, proton source, tertiary amine | SHELL OIL COMPANY (US) | 1992-06-23 | — | — | US | disclosed |
| US-5099062-A | Reaction of acetylenic compound with carbon monoxide to form unsaturated monomers | SHELL OIL COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0441446-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0441447-A1 | Carbonylation catalyst process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0441445-A2 | Preparation of amides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0386833-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-09-12 | — | — | EP | disclosed |