Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157639 | 1.00 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2TP53ATM | |
| SCHEMBL746755 | 0.97 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2TP53ATM | |
| SCHEMBL9384923 | 0.97 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2TP53ATM | |
| SCHEMBL16681177 | 0.95 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2TP53ATM | |
| SCHEMBL2079639 | 0.89 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2TP53TSHR | |
| SCHEMBL989416 | 0.89 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2TP53TSHR | |
| SCHEMBL11859589 | 0.89 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2TP53TSHR | |
| SCHEMBL29058806 | 0.86 | TP53 (0.32) | HCAR2TP53TSHR | |
| Acrylic Acid SCHEMBL28914099 | 0.82 | HCAR2 (0.47) | HCAR2TP53TSHRALDH1A1 | |
| SCHEMBL27371375 | 0.81 | TP53 (0.44) | TP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999065337-A1 | DIETARY SUPPLEMENT FOR POST-MENOPAUSAL WOMEN | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 1999-12-23 | — | — | WO | claimed |