Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793444 | 0.84 | TSHR (0.41) | TSHRCA1FOLH1NAALAD2 | |
| SCHEMBL270073 | 0.84 | TSHR (0.41) | TSHRCA1FOLH1NAALAD2 | |
| SCHEMBL28700075 | 0.83 | SMN1; SMN2 (0.33) | CA1 | |
| SCHEMBL8458239 | 0.81 | CHRM1 (0.39) | TSHRCA1 | |
| SCHEMBL8459086 | 0.80 | TSHR (0.39) | TSHRECE1CA1 | |
| Alcohol SCHEMBL8390981 | 0.79 | TSHR (0.38) | TSHRCA1FOLH1NAALAD2MMP1 | |
| SCHEMBL888827 | 0.79 | — | — | |
| SCHEMBL269836 | 0.79 | — | — | |
| SCHEMBL12388848 | 0.79 | — | — | |
| SCHEMBL105681 | 0.78 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646605-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5468704-A | Comprising titanium halide or halogen alcoholate supported on magnesium halide and a diketone electron donor; preparing polypropylene of high isotacticity | MONTELL NORTH AMERICA INC. (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0646605-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1995-04-05 | — | — | EP | disclosed |