Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462678 | 0.83 | GRIN2D (0.68) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8462734 | 0.83 | GRIN2D (0.46) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8464339 | 0.81 | GRIN2D (0.45) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8464770 | 0.81 | GRIN2D (0.45) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8460487 | 0.80 | GRIN2D (0.44) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8463657 | 0.79 | CYP2D6 (0.48) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8461633 | 0.79 | MCL1 (0.47) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8462817 | 0.79 | GRIN2D (0.40) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8464724 | 0.78 | IDO1 (0.55) | GRIN2DGRIN2AGRIN2BGRIN2CTSHR | |
| SCHEMBL8463776 | 0.78 | KDM4E (0.71) | GRIN2DGRIN2AGRIN2BGRIN2CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |