Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 6/20 | 0.49 |
| ▸ | F3 | P13726 | 6/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | BID | P55957 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464639 | 1.00 | F7 (0.49) | F7F3ALOX15HSD17B10MMP2 | |
| SCHEMBL8463573 | 0.92 | KAT8 (0.46) | SAE1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL8464839 | 0.82 | F7 (0.53) | F7F3ALOX15HSD17B10MMP2 | |
| SCHEMBL8464842 | 0.82 | F7 (0.53) | F7F3ALOX15HSD17B10MMP2 | |
| SCHEMBL8460575 | 0.81 | KAT8 (0.58) | F7F3ALOX15HSD17B10MMP2 | |
| SCHEMBL8460579 | 0.81 | KAT8 (0.58) | F7F3ALOX15HSD17B10MMP2 | |
| SCHEMBL11800974 | 0.80 | KAT8 (0.56) | SAE1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL8463357 | 0.80 | F7 (0.49) | F7F3ALOX15HSD17B10MMP2 | |
| SCHEMBL8463353 | 0.80 | F7 (0.49) | F7F3ALOX15HSD17B10MMP2 | |
| SCHEMBL9700182 | 0.77 | KAT8 (0.53) | SAE1BIDBCL2L1MCL1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |