Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 4/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016965 | 0.91 | CNR1 (0.59) | CNR1CNR2GABRA2GABRB2POLB | |
| Hydrochloric Acid SCHEMBL2020512 | 0.90 | CNR1 (0.58) | CNR1CNR2GABRA2GABRB2POLB | |
| SCHEMBL8470259 | 0.88 | CNR1 (0.54) | CNR1CNR2GABRA2GABRB2POLB | |
| SCHEMBL12527317 | 0.83 | CNR1 (0.52) | CNR1CNR2LMNAPDE5A | |
| SCHEMBL4598704 | 0.81 | CNR1 (0.60) | CNR1CNR2GABRA2GABRB2LMNA | |
| SCHEMBL2015954 | 0.81 | CNR2 (0.62) | CNR1CNR2GABRA2GABRB2LMNA | |
| SCHEMBL8464834 | 0.81 | CNR1 (0.49) | CNR1CNR2AKR1C3PDE5A | |
| SCHEMBL2018944 | 0.80 | CNR1 (0.55) | CNR1CNR2POLBLMNATP53 | |
| SCHEMBL4607380 | 0.80 | CNR1 (0.61) | CNR1CNR2TSHRKMT2A | |
| SCHEMBL2288238 | 0.80 | CNR1 (0.61) | CNR1CNR2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |