Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642573 | 0.88 | ESR2 (0.42) | ESR2 | |
| SCHEMBL16105204 | 0.83 | ESR2 (0.48) | ESR2 | |
| SCHEMBL10771351 | 0.83 | ESR2 (0.38) | ESR2 | |
| SCHEMBL15847334 | 0.81 | ESR2 (0.39) | ESR2 | |
| SCHEMBL18543669 | 0.79 | ESR2 (0.38) | ESR2 | |
| SCHEMBL19543501 | 0.77 | ESR2 (0.37) | ESR2 | |
| SCHEMBL18543685 | 0.77 | ESR2 (0.37) | ESR2 | |
| SCHEMBL10475887 | 0.77 | ESR2 (0.37) | ESR2 | |
| SCHEMBL8468407 | 0.77 | ESR2 (0.37) | ESR2 | |
| SCHEMBL14358589 | 0.77 | CYP1A2 (0.38) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5824661-A | TREATMENT OF OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-20 | — | — | US | disclosed |