Butadiene

Butadiene

SCHEMBL8465755

C=CC(=O)OCC(CC)CCCC.C=CC=C

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.94
CYP3A4 P08684 5/20 0.57
TDP1 Q9NUW8 2/20 0.57
ATM Q13315 1/20 0.57
HPGD P15428 1/20 0.51
ALDH1A1 P00352 6/20 0.50
CA2 P00918 3/20 0.50
RECQL P46063 1/20 0.48
LMNA P02545 3/20 0.46
MAPK1 P28482 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP14 P50281 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29596375 0.97 TSHR (1.00) TSHRCYP3A4TDP1ATMHPGD
SCHEMBL16765797 0.97 TSHR (1.00) TSHRCYP3A4TDP1ATMHPGD
SCHEMBL14869 0.97 TSHR (1.00) TSHRCYP3A4TDP1ATMHPGD
SCHEMBL20609794 0.97 TSHR (1.00) TSHRCYP3A4TDP1ATMHPGD
Benzene SCHEMBL8735839 0.95 TSHR (0.85) TSHRCYP3A4TDP1ATMHPGD
Bromide SCHEMBL20490069 0.95 TSHR (0.97) TSHRCYP3A4TDP1ATMHPGD
Fluoride SCHEMBL28158331 0.95 TSHR (0.97) TSHRCYP3A4TDP1ATMHPGD
Hydrochloric Acid SCHEMBL10432463 0.95 TSHR (0.97) TSHRCYP3A4TDP1ATMHPGD
SCHEMBL31738423 0.95 TSHR (0.97) TSHRCYP3A4TDP1ATMHPGD
Ethylene SCHEMBL670832 0.95 TSHR (0.97) TSHRCYP3A4TDP1ATMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075338-B Two-pack polyurethane adhesive composition 横滨橡胶株式会社 2020-11-27 CN disclosed
US-10611876-B2 Epoxy-amine adduct, thermoplastic resin composition, sizing agent, sizing agent coated carbon fiber, and fiber-reinforced composite material DAICEL CORPORATION (JP) 2020-04-07 US disclosed
EP-3257792-B1 BELT NITTA CORP (JP) 2019-03-27 EP disclosed
EP-2692802-B1 BELT NITTA CORP (JP) 2019-03-13 EP disclosed
EP-3438176-A1 INJECTION-MOLDED FOAM OF RESIN COMPOSITION WITH SATISFACTORY SURFACE PROPERTY AND CAPABLE OF WEIGHT REDUCTION AND RIB DESIGN Kaneka Corporation (JP) 2019-02-06 EP disclosed
US-20190031851-A1 INJECTION-MOLDED FOAM OF RESIN COMPOSITION WITH SATISFACTORY SURFACE PROPERTY AND CAPABLE OF WEIGHT REDUCTION AND RIB DESIGN KANEKA CORPORATION (JP) 2019-01-31 US disclosed
EP-3127932-B1 EPOXY-AMINE ADDUCT, THERMOPLASTIC RESIN COMPOSITION, SIZING AGENT, SIZING AGENT COATED CARBON FIBER, AND FIBER-REINFORCED COMPOSITE MATERIAL DAICEL CORP (JP) 2018-10-24 EP disclosed
US-9862825-B2 Thermoplastic resin composition having high durability NITTA CORPORATION (JP) 2018-01-09 US disclosed
EP-3257792-A1 BELT Nitta Corporation (JP) 2017-12-20 EP disclosed
US-20170313878-A1 THERMOPLASTIC RESIN COMPOSITION HAVING HIGH DURABILITY NITTA CORPORATION (JP) 2017-11-02 US disclosed
EP-2692801-B1 THERMOPLASTIC RESIN COMPOSITION HAVING HIGH DURABILITY NITTA CORP (JP) 2016-08-24 EP disclosed
EP-2886286-A1 MOULDED BODY HAVING SPECIFIC CROSS-SECTIONAL STRUCTURE Kaneka Corporation (JP) 2015-06-24 EP disclosed
US-20150165659-A1 MOULDED BODY HAVING SPECIFIC CROSS-SECTIONAL STRUCTURE KANEKA CORPORATION (JP) 2015-06-18 US disclosed
EP-2692801-A1 THERMOPLASTIC RESIN COMPOSITION HAVING HIGH DURABILITY Nitta Corporation (JP) 2014-02-05 EP disclosed
EP-2692802-A1 BELT Nitta Corporation (JP) 2014-02-05 EP disclosed
US-20140017429-A1 THERMOPLASTIC RESIN COMPOSITION HAVING HIGH DURABILITY NITTA CORPORATION (JP) 2014-01-16 US disclosed
US-20140018501-A1 BELT NITTA CORPORATION (JP) 2014-01-16 US disclosed
EP-0687689-B1 Agglomerating agent latex with bound poly(ethylene oxide) GEN ELECTRIC (US) 1999-08-04 EP disclosed
EP-0687689-A1 Agglomerating agent latex with bound poly(ethylene oxide) GENERAL ELECTRIC COMPANY (US) 1995-12-20 EP disclosed
US-5470895-A Agglomeration of rubber particles of unsaturated monomer and vinyl functional polyoxyethylene copolymers and mixing with latex GENERAL ELECTRIC COMPANY (US) 1995-11-28 US disclosed