Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.65 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846149 | 0.97 | TRPV1 (0.60) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846496 | 0.85 | TRPV1 (0.56) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846812 | 0.85 | NPC1 (0.63) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846300 | 0.84 | KDR (0.67) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846030 | 0.84 | KDR (0.67) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846074 | 0.84 | KDR (0.67) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846379 | 0.84 | KDR (0.67) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL845928 | 0.84 | TRPV1 (0.62) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846482 | 0.84 | TRPV1 (0.62) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL846368 | 0.84 | TRPV1 (0.62) | TRPV1KDRNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | claimed |