Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | PTPRC | P08575 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95004 | 0.93 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL13851887 | 0.80 | MAPT (0.44) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL29406202 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL18537836 | 0.78 | TYMS (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL41631 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL1105125 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL11919733 | 0.78 | TYMS (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL41632 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL29391183 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10TYMS | |
| SCHEMBL24186408 | 0.77 | MAPT (0.47) | MAPTKDM4EALDH1A1HSD17B10TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759040-B1 | CARBONYL CONTAINING COMPOUNDS AND THEIR DERIVATIVES AS MULTI-FUNCTIONAL FUEL AND LUBE ADDITIVES | EXXON RESEARCH ENGINEERING CO (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5646098-A | Carbonyl containing compounds and their derivatives as multi-functional fuel and lube additives | EXXON CHEMICAL PATENTS INC (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0759040-A1 | CARBONYL CONTAINING COMPOUNDS AND THEIR DERIVATIVES AS MULTI-FUNCTIONAL FUEL AND LUBE ADDITIVES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995031488-A1 | CARBONYL CONTAINING COMPOUNDS AND THEIR DERIVATIVES AS MULTI-FUNCTIONAL FUEL AND LUBE ADDITIVES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1995-11-23 | — | — | WO | disclosed |