Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466278 | 0.96 | TTR (0.37) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL8049894 | 0.93 | TTR (0.39) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL8385234 | 0.86 | TTR (0.35) | TTRCYP1A2MYC | |
| SCHEMBL8049976 | 0.85 | TTR (0.39) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL21624952 | 0.76 | CA12 (0.39) | TTRCYP1A2MYC | |
| SCHEMBL6262273 | 0.76 | TTR (0.40) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL1269675 | 0.73 | TTR (0.52) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL27412158 | 0.71 | MYC (0.35) | TTRMYCFABP4CCNA2CDK2 | |
| SCHEMBL8818051 | 0.71 | TSHR (0.38) | TTRCYP1A2MYCFABP4CCNA2 | |
| Hydrochloric Acid SCHEMBL628234 | 0.71 | TTR (0.50) | TTRCYP1A2MYCFABP4CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922634-A | HYDROFORMYLATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5847200-A | Substituted diphosphines and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0811424-A2 | Catalyst systems based on Rhodium complexes with diphosphine ligands and their use for the preparation of aldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0807636-A1 | Substituted diphosphines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |