Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466521 | 1.00 | TSHR (0.50) | TSHRALDH1A1FASNTRPA1PPARA | |
| SCHEMBL25186089 | 0.98 | TSHR (0.54) | TSHRALDH1A1FASNTRPA1KDM4E | |
| SCHEMBL7915169 | 0.98 | TSHR (0.54) | TSHRALDH1A1FASNTRPA1KDM4E | |
| SCHEMBL25182570 | 0.98 | TSHR (0.54) | TSHRALDH1A1FASNTRPA1KDM4E | |
| SCHEMBL10630177 | 0.98 | TSHR (0.54) | TSHRALDH1A1FASNTRPA1KDM4E | |
| SCHEMBL10630183 | 0.98 | TSHR (0.54) | TSHRALDH1A1FASNTRPA1KDM4E | |
| SCHEMBL25178083 | 0.95 | TSHR (0.48) | TSHRALDH1A1FASNTRPA1PPARA | |
| SCHEMBL7185169 | 0.93 | TSHR (0.46) | TSHRALDH1A1FASNTRPA1PPARA | |
| SCHEMBL7185175 | 0.93 | TSHR (0.46) | TSHRALDH1A1FASNTRPA1PPARA | |
| SCHEMBL25178077 | 0.85 | TSHR (0.56) | TSHRALDH1A1FASNKDM4ECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564039-B1 | Polymeric thermoplastic composition based on polyphenylene ether and an impact-resistant vinyl aromatic copolymer | ENICHEM SPA (IT) | 1999-12-29 | — | — | EP | disclosed |
| EP-0560447-B1 | Thermoplastic composition based on polyphenylene ether and polyamide | ENICHEM SPA (IT) | 1998-05-13 | — | — | EP | disclosed |
| EP-0534543-B1 | Polyphenylene ether containing reactive end groups, process for preparing it and relevant thermoplastic compositions | ENICHEM SPA (IT) | 1997-12-17 | — | — | EP | disclosed |
| EP-0528477-B1 | Toughened thermoplastic compositions based on polyphenylene ether and polyamide | ENICHEM SPA (IT) | 1997-05-21 | — | — | EP | disclosed |
| EP-0574054-B1 | Flame retardant thermoplastic composition containing an impact-resistant vinyl aromatic copolymer | ENICHEM SPA (IT) | 1997-03-05 | — | — | EP | disclosed |
| EP-0618268-A1 | Thermoplastic composition based on polyphenylene ether and modified polyamide | ENICHEM S.p.A. (IT) | 1994-10-05 | — | — | EP | disclosed |
| EP-0574054-A2 | Flame retardant thermoplastic composition containing an impact-resistant vinyl aromatic copolymer | ENICHEM S.p.A. (IT) | 1993-12-15 | — | — | EP | disclosed |
| EP-0564039-A2 | Polymeric thermoplastic composition based on polyphenylene ether and an impact-resistant vinyl aromatic copolymer | ENICHEM S.p.A. (IT) | 1993-10-06 | — | — | EP | disclosed |
| EP-0560447-A1 | Thermoplastic composition based on polyphenylene ether and polyamide | ENICHEM S.p.A. (IT) | 1993-09-15 | — | — | EP | disclosed |
| US-5210125-A | Elastomeric copolymer of vinyl aromatic polymer grafted on olefinic elastomer, organic diisocyanate | ECP ENICHEM POLIMERI S.R.L. (IT) | 1993-05-11 | — | — | US | disclosed |
| EP-0534543-A1 | Polyphenylene ether containing reactive end groups, process for preparing it and relevant thermoplastic compositions | ENICHEM S.p.A. (IT) | 1993-03-31 | — | — | EP | disclosed |
| EP-0528477-A1 | Toughened thermoplastic compositions based on polyphenylene ether and polyamide | ENICHEM S.p.A. (IT) | 1993-02-24 | — | — | EP | disclosed |