Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503415 | 0.97 | TSHR (0.60) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL828473 | 0.96 | TSHR (0.63) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL7078308 | 0.91 | TSHR (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL829228 | 0.91 | TSHR (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL829039 | 0.91 | TSHR (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL17967704 | 0.91 | TSHR (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL828469 | 0.91 | TSHR (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL4138132 | 0.91 | TSHR (0.61) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL828217 | 0.91 | TSHR (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL829282 | 0.91 | TSHR (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613916-B1 | Moulding composition based on anhydride-group terminated polyarylene ethers | BASF AG (DE) | 1999-05-06 | — | — | EP | claimed |
| US-5457169-A | Molding materials based on polyarylene ethers having terminal anhydride groups | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | claimed |
| WO-2014152543-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel IP & Holding GmbH (DE) | 2014-09-25 | — | — | WO | disclosed |
| US-20140264165-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2760910-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel AG&Co. KGAA (DE) | 2014-08-06 | — | — | EP | disclosed |
| US-20140209951-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel IP & Holding GmbH (DE) | 2014-07-31 | — | — | US | disclosed |
| WO-2013049154-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL AG & CO. KGAA (DE) | 2013-04-04 | — | — | WO | disclosed |
| US-5457169-A | Molding materials based on polyarylene ethers having terminal anhydride groups | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |