SCHEMBL8467283

SCHEMBL8467283

Fc1ccccc1F.Nc1ccccc1F

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.53
ALOX15 P16050 2/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 5/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TSHR P16473 4/20 0.41
ACHE P22303 1/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
NFE2L2 Q16236 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33295 0.97
SCHEMBL29410382 0.97
Hydrochloric Acid SCHEMBL3152989 0.94
SCHEMBL3595240 0.94
Hydrochloric Acid SCHEMBL4376685 0.94 CYP3A4 (0.53) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Bromide SCHEMBL25169235 0.94
Iodide SCHEMBL28579873 0.94
Methane SCHEMBL1702520 0.94
SCHEMBL358525 0.94
Nitrogen SCHEMBL28948708 0.91 CYP3A4 (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0900180-A1 PROCESS FOR THE PREPARATION OF FLUORO COMPOUNDS FROM THE CORRESPONDING AMINES Rhodia Limited (GB) 1999-03-10 EP disclosed
WO-1997041083-A1 PROCESS FOR THE PREPARATION OF FLUORO COMPOUNDS FROM THE CORRESPONDING AMINES RHODIA LIMITED (GB) 1997-11-06 WO disclosed