SCHEMBL846775

SCHEMBL846775

C[C@H]1COC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14748794 1.00
SCHEMBL576623 1.00
SCHEMBL22769627 0.97 CYP3A4 (0.46)
SCHEMBL14284250 0.79 KMT2A (0.38)
SCHEMBL22769621 0.79 CYP3A4 (0.37)
SCHEMBL9053223 0.75
SCHEMBL15095488 0.75
SCHEMBL22769628 0.74 SMN1; SMN2 (0.50)
SCHEMBL12176979 0.73 CYP3A4 (0.33)
SCHEMBL7906063 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same NOVOMER, INC. (US) 2023-11-14 US disclosed
WO-2023126676-A1 HOT MELT ADHESIVE COMPOSITIONS BASED ON POLY(ALPHA-METHYL-BETA-PROPIOLACTONE) POLYMERS OR DERIVATIVES AND METHODS FOR USING THEM BOSTIK SA (FR) 2023-07-06 WO disclosed
WO-2023126676-A1 HOT MELT ADHESIVE COMPOSITIONS BASED ON POLY(ALPHA-METHYL-BETA-PROPIOLACTONE) POLYMERS OR DERIVATIVES AND METHODS FOR USING THEM BOSTIK SA (FR) 2023-07-06 WO disclosed
US-20200331876-A1 ISOCYANATES, DERIVATIVES, AND PROCESSES FOR PRODUCING THE SAME NOVOMER, INC. 2020-10-22 US disclosed
US-10676426-B2 Acrylonitrile derivatives from epoxide and carbon monoxide reagents NOVOMER, INC. (US) 2020-06-09 US disclosed
US-20190076835-A1 PROCESSSES USING MULTIFUNCTIONAL CATALYSTS NOVOMER, INC. 2019-03-14 US disclosed
US-20190002400-A1 Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents NOVOMER, INC. (US) 2019-01-03 US disclosed
US-20170355689-A1 HEPATITIS C VIRUS INHIBITOR BRISTOL MYERS SQUIBB CO (US) 2017-12-14 US disclosed
US-20170320833-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-11-09 US disclosed
US-20170283453-A1 COFACTOR ANALOGUES FOR METHYLTRANSFERASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2017-10-05 US disclosed
US-20110237636-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-09-29 US disclosed
US-20110195044-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-08-11 US disclosed
US-20110130433-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-06-02 US disclosed
US-20110098327-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-04-28 US disclosed
US-7425635-B2 Prodrugs and conjugates of thiol- and selenol-containing compounds and methods of use thereof UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2008-09-16 US disclosed
EP-1921062-A2 Amino acid derivatives as HIV aspartyl protease inhibitors Ambrilia Biopharma Inc. (CA) 2008-05-14 EP disclosed
EP-1263716-B1 AMINO ACID DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS AMBRILIA BIOPHARMA INC (CA) 2008-01-02 EP disclosed
US-20070093413-A1 Histone deacetylases, and uses related thereto HARVARD UNIVERSITY OTI (US) 2007-04-26 US disclosed
US-20070088086-A1 Method of using synthetic L-Se-methylselenocysteine as a nutriceutical and a method of its synthesis PHARMASE, INCORPORATED 2007-04-19 US disclosed
WO-2003045378-A1 AMINO ACID DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. (US) 2003-06-05 WO disclosed