SCHEMBL8467775

SCHEMBL8467775

C1CCC(c2nc(NCCN3CCNCC3)nc(NCCN3CCNCC3)n2)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.50
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
ALOX15 P16050 2/20 0.34
TSHR P16473 2/20 0.34
PIM1 P11309 1/20 0.34
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HRH4 Q9H3N8 1/20 0.33
LMNA P02545 1/20 0.33
PRKCZ Q05513 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853170 0.90 CA1 (0.46) RAD52CA1CA2CA9CYP3A4
SCHEMBL8467788 0.83 MEN1 (0.53) CYP3A4CYP2D6MEN1KMT2ATSHR
SCHEMBL8853168 0.75 MEN1 (0.57) CYP3A4CYP2D6MEN1KMT2ATSHR
SCHEMBL8465816 0.75 HRH3 (0.45) CHRM3PIM1
SCHEMBL8468626 0.72 SLC29A1 (0.45) MEN1KMT2AALDH1A1
SCHEMBL8853155 0.69 CA1 (0.42) RAD52CA1CA2CA9CYP3A4
SCHEMBL8852915 0.69 CA1 (0.39) RAD52CA1CA2CA9CYP3A4
SCHEMBL8523679 0.67 MEN1 (0.44) MEN1KMT2ATSHRALDH1A1LMNA
SCHEMBL8466188 0.67 TSHR (0.33) HSD17B10CHRM3TSHRALDH1A1PDE10A
SCHEMBL8468597 0.67 MEN1 (0.47) MEN1KMT2ATSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869184-A RESIN RAW MATERIALS FOR PAINTS, ADHESIVES MITSUI TOATSU CHEMICALS, INC. (JP) 1999-02-09 US disclosed
US-5744504-A AMINO RESIN; THERMOSETTING MOLDING MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-04-28 US disclosed