Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.57 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532484 | 1.00 | CD274 (0.59) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| Hydrochloric Acid SCHEMBL587493 | 0.98 | CD274 (0.58) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| SCHEMBL29558442 | 0.93 | HTR2C (0.57) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| SCHEMBL746109 | 0.93 | HTR2C (0.57) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| Hydrochloric Acid SCHEMBL1124555 | 0.91 | HTR2C (0.55) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| Hydrochloric Acid SCHEMBL31062521 | 0.91 | HTR2C (0.55) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| Oxalic Acid SCHEMBL7199943 | 0.91 | CD274 (0.52) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| SCHEMBL29758918 | 0.89 | KCNH2 (0.54) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| SCHEMBL4859823 | 0.89 | KCNH2 (0.54) | CD274HTR2CHTR2AHTR2BKCNH2 | |
| Bromide SCHEMBL19644475 | 0.89 | CD274 (0.51) | CD274HTR2CHTR2AHTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |