Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468315 | 0.88 | MAOB (0.50) | GFERMAOBMAOATDP1ALDH1A1 | |
| SCHEMBL2408286 | 0.82 | GFER (0.59) | GFERMAOBMAOATDP1ALDH1A1 | |
| SCHEMBL17100984 | 0.78 | GFER (0.54) | GFERMAOBMAOATDP1ALDH1A1 | |
| SCHEMBL20634143 | 0.78 | ESR1 (0.54) | ALDH1A1CYP3A4TSHRTAAR1CYP1A2 | |
| SCHEMBL6729364 | 0.77 | TSHR (0.48) | ALDH1A1TSHRCYP1A2 | |
| SCHEMBL17807999 | 0.77 | TSHR (0.48) | ALDH1A1TSHRCYP1A2 | |
| SCHEMBL8100935 | 0.77 | CYP3A4 (0.58) | GFERMAOBMAOATDP1ALDH1A1 | |
| SCHEMBL27906651 | 0.77 | GFER (0.52) | GFERMAOBMAOATDP1ALDH1A1 | |
| SCHEMBL18789292 | 0.77 | GFER (0.65) | GFERMAOBMAOATDP1ALDH1A1 | |
| SCHEMBL8468444 | 0.76 | MAOB (0.55) | MAOBMAOAALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5824661-A | TREATMENT OF OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-20 | — | — | US | disclosed |