SCHEMBL8468494

SCHEMBL8468494

CCC1NCC(CS)CC1C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GANAB Q14697 1/20 0.36
GBA1 P04062 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23131541 0.68 GANAB (0.36) GANABGBA1
SCHEMBL8468490 0.68 GANAB (0.36) GANABGBA1
SCHEMBL8467749 0.66
SCHEMBL23718375 0.64 GANAB (0.36) GANABGBA1
SCHEMBL6405177 0.64 GANAB (0.40) GANABGBA1
SCHEMBL24106621 0.63
SCHEMBL24965964 0.63
SCHEMBL14596390 0.63 GANAB (0.43) GANABGBA1
SCHEMBL25088329 0.63 MGAM (0.34)
SCHEMBL25844367 0.63 GANAB (0.34) GANABGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869471-A Methods for the treatment of arthritis using phosphonates and NSAIDS THE PROCTOR & GAMBLE COMPANY (US) 1999-02-09 US disclosed
US-5856314-A Thio-substituted, Nitrogen-containing, heterocyclic phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism THE PROCTER & GAMBLE COMPANY (US) 1999-01-05 US disclosed