Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966841 | 1.00 | PDE4A (0.50) | PDE4AKDM4EGAACTSKNPSR1 | |
| SCHEMBL7720129 | 0.87 | KDM4E (0.43) | PDE4AKDM4EGAACTSKNPSR1 | |
| SCHEMBL5909680 | 0.87 | PDE4A (0.56) | PDE4AKDM4EGAACTSKRAB9A | |
| SCHEMBL3296576 | 0.84 | PDE4A (0.64) | PDE4AKDM4EGAACTSKNPSR1 | |
| SCHEMBL18557112 | 0.74 | PDE4A (0.82) | PDE4AKDM4EGAACTSKNPSR1 | |
| SCHEMBL20402878 | 0.74 | PDE4A (0.82) | PDE4AKDM4EGAACTSKNPSR1 | |
| SCHEMBL18557113 | 0.74 | PDE4A (0.82) | PDE4AKDM4EGAACTSKNPSR1 | |
| SCHEMBL8053847 | 0.74 | PDE4A (0.59) | PDE4AKDM4EGAANPSR1RAB9A | |
| SCHEMBL17070790 | 0.74 | PDE4A (0.55) | PDE4AKDM4EGAACTSKNPSR1 | |
| SCHEMBL6640516 | 0.74 | PDE4A (0.55) | PDE4AKDM4EGAANPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869184-A | RESIN RAW MATERIALS FOR PAINTS, ADHESIVES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1999-02-09 | — | — | US | disclosed |