Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468660 | 1.00 | MEN1 (0.61) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL3856093 | 0.85 | MEN1 (0.68) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL7226427 | 0.82 | MEN1 (0.65) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL7951355 | 0.82 | MEN1 (0.65) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL7952672 | 0.82 | MEN1 (0.65) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL3968577 | 0.81 | MEN1 (0.56) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL14341350 | 0.81 | MEN1 (0.56) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL14341349 | 0.81 | MEN1 (0.56) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL7951338 | 0.80 | MEN1 (0.62) | MEN1KMT2AHTR5AOPRM1KDM1A | |
| SCHEMBL8013929 | 0.80 | MEN1 (0.66) | MEN1KMT2AHTR5AOPRM1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866708-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0866708-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997017969-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |