O-Tolylamine

O-Tolylamine

SCHEMBL8469060

Cc1ccccc1N.Cc1ccccc1N

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.94
TDP1 Q9NUW8 5/20 0.94
CD44 P16070 1/20 0.60
TSHR P16473 6/20 0.56
CASP1 P29466 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
ALOX15 P16050 2/20 0.56
ACHE P22303 2/20 0.56
CASP7 P55210 1/20 0.56
PIK3CA P42336 1/20 0.53
ALDH1A1 P00352 5/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TP53 P04637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
GAA P10253 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
ADRA2B P18089 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Tolylamine SCHEMBL15789 1.00
O-Tolylamine SCHEMBL29441724 1.00
O-Tolylamine SCHEMBL9613766 1.00 CYP3A4 (0.94) CYP3A4TDP1CD44TSHRCASP1
O-Tolylamine SCHEMBL31145800 1.00
O-Tolylamine SCHEMBL8602819 0.97
O-Tolylamine SCHEMBL9498667 0.97
O-Tolylamine SCHEMBL22471782 0.97 CYP3A4 (0.88) CYP3A4TDP1CD44TSHRCASP1
O-Tolylamine SCHEMBL21494153 0.97
O-Tolylamine SCHEMBL439510 0.97
O-Tolylamine SCHEMBL2171758 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110234722-A Two-part adhesive composition 株式会社LG化学 2019-09-13 CN disclosed
EP-3353270-A1 FUEL COMPOSITIONS SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) 2018-08-01 EP disclosed
WO-2017050777-A1 FUEL COMPOSITIONS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2017-03-30 WO disclosed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US disclosed
US-5593638-A Apparatus for estimating the change in an analyte from hemolysis in a fluid sample I-STAT CORPORATION (US) 1997-01-14 US disclosed
US-4480128-A USING ZEOLITE ISOMERIZATION CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed
US-4269763-A STABILIZERS FOR DIENE RUBBERS PREPARED BY REACTING HYDROQUINONE WITH A MIXTURE OF O-TOLUIDINE, XYLIDENE MIXTURE AND ANILINE; MELTING POINTS; OXIDATION AND OZONE RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-05-26 US disclosed