Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzidine SCHEMBL28611518 | 0.65 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL320609 | 0.65 | MEN1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL27981 | 0.65 | — | — | |
| Benzidine SCHEMBL28721485 | 0.63 | TDP1 (0.69) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL8526630 | 0.63 | TDP1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL5097 | 0.63 | — | — | |
| Ethane SCHEMBL5726956 | 0.62 | MEN1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| Methylamine SCHEMBL27939730 | 0.62 | MAPT (0.73) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| Methyl Alcohol SCHEMBL9437744 | 0.62 | MAPT (0.73) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL357435 | 0.61 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999063003-A1 | LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS | LOCTITE CORPORATION (US) | 1999-12-09 | — | — | WO | claimed |
| WO-1999063003-A1 | LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS | LOCTITE CORPORATION (US) | 1999-12-09 | — | — | WO | disclosed |