SCHEMBL846924

SCHEMBL846924

N#Cc1cc2ccccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 1.00
KDM4E B2RXH2 3/20 0.44
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
FLT3 P36888 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
MGLL Q99685 1/20 0.44
HPGD P15428 2/20 0.42
POLB P06746 2/20 0.42
TYR P14679 1/20 0.42
DAO P14920 1/20 0.42
AKR1B1 P15121 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PSMB8 P28062 1/20 0.42
CA2 P00918 2/20 0.41
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.40
PKM P14618 1/20 0.40
MAOB P27338 4/20 0.40
RAB9A P51151 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30142419 1.00 CYP2A6 (1.00) CYP2A6KDM4EHSD17B10TDP1FLT3
SCHEMBL3672137 0.85 CYP2A6 (0.72) CYP2A6KDM4EHSD17B10TDP1FLT3
SCHEMBL1995148 0.83 CYP2A6 (0.71) CYP2A6KDM4EHSD17B10TDP1HPGD
SCHEMBL22074285 0.82 CYP2A6 (0.68) CYP2A6KDM4EHSD17B10TDP1FLT3
SCHEMBL96257 0.78 CYP2A6 (0.64) CYP2A6KDM4EHSD17B10TDP1FLT3
SCHEMBL3714418 0.78 CYP2A6 (0.64) CYP2A6KDM4EHSD17B10TDP1FLT3
SCHEMBL2855183 0.78 CYP2A6 (0.64) CYP2A6KDM4EHSD17B10TDP1FLT3
SCHEMBL1778078 0.78 CYP2A6 (0.64) CYP2A6KDM4EHSD17B10TDP1FLT3
SCHEMBL4816114 0.78 CYP2A6 (0.64) CYP2A6KDM4EHSD17B10TDP1FLT3
Hydrochloric Acid SCHEMBL9294517 0.78 CYP2A6 (0.60) CYP2A6KDM4EHSD17B10TDP1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120028308-A Small molecule Raman probe, bar code probe, encoding method and application thereof 北京大学 2025-05-23 CN claimed
CN-103751943-A Fire extinguishing composition containing nitrogenous organic compound XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-04-30 CN claimed
JP-9124631-A None JP disclosed
WO-2026102105-A1 FUNCTIONAL POLYBUTADIENE AND CARBON BLACK IN RUBBER COMPOUNDS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2026-05-15 WO disclosed
CN-120028308-A Small molecule Raman probe, bar code probe, encoding method and application thereof 北京大学 2025-05-23 CN disclosed
CN-114761410-B Pyrrolopyrimidinone compounds and application thereof 广州必贝特医药股份有限公司 2023-08-25 CN disclosed
CN-116262753-A Novel PIM kinase inhibitors 杭州邦顺制药有限公司 2023-06-16 CN disclosed
CN-113150003-B Organic light-emitting compound and organic electroluminescent device 北京绿人科技有限责任公司 2023-04-07 CN disclosed
US-11512148-B2 Composition including multiple terminally functionalized polymers BRIDGESTONE CORPORATION (JP) 2022-11-29 US disclosed
CN-112574054-B Efficient nitriding reagent and application thereof 北京大学 2022-10-14 CN disclosed
WO-2022213932-A1 PYRROLOPYRIMIDINONE COMPOUND AND APPLICATION THEREOF 广州必贝特医药股份有限公司 2022-10-13 WO disclosed
EP-1055724-A1 MICROORGANISMS AND PROCESS FOR PRODUCING AMIDE COMPOUNDS Daicel Chemical Industries, Ltd. (JP) 2000-11-29 EP disclosed
WO-2000012468-A1 AN IMPROVED SYNTHESIS OF 3-HYDROXY-4-AMINO-BENZONITRILE SMITHKLINE BEECHAM CORPORATION (US) 2000-03-09 WO disclosed
WO-1999054284-A1 ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-28 WO disclosed
WO-1999052875-A1 AMINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS SOMATOSTATIN RECEPTOR ANTAGONISTS OR AGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-10-21 WO disclosed
JP-H09124631-A BENZOFURAN DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME SHANXI CHUIYAKU KENKYUIN 1997-05-13 JP disclosed
US-5354769-A Treatment of anorexia SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1994-10-11 US disclosed
US-5310930-A Cyclization of the carboximidate salt SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) (FR) 1994-05-10 US disclosed
EP-0007719-A2 Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives FBC LIMITED (GB) 1980-02-06 EP disclosed
US-4001426-A HAVING CORONARY VASODILATOR ACTIVITY SMITHKLINE CORPORATION (US) 1977-01-04 US disclosed