Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489196 | 1.00 | MAPK8 (0.35) | MAPK8ATMPARP1EPHX2MAPT | |
| SCHEMBL4734231 | 0.85 | — | — | |
| SCHEMBL1051214 | 0.82 | MAPT (0.33) | MAPK8EPHX2MAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL12928724 | 0.82 | EPHX2 (0.33) | MAPK8EPHX2MAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL1051212 | 0.82 | MAPT (0.33) | MAPK8EPHX2MAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL12928726 | 0.82 | EPHX2 (0.33) | MAPK8EPHX2MAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL19321045 | 0.82 | MAPT (0.33) | MAPK8EPHX2MAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL1045346 | 0.80 | EPHX2 (0.35) | MAPK8EPHX2MAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL1045347 | 0.80 | EPHX2 (0.35) | MAPK8EPHX2MAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL31661949 | 0.77 | EPHX1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764099-A2 | Diaminoalcohol derivatives for the treatment of Alzheimer, malaria, HIV | Speedel Experimenta AG (CH) | 2007-03-21 | — | — | EP | disclosed |