Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 15/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 13/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 10/20 | 0.50 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691441 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL6694946 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL8469706 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL8467701 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL6700226 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL8469491 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL8468226 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL6692700 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL6693342 | 0.98 | LPAR3 (0.58) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL6695658 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942470-A | OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0459656-B1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES INC (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0459656-A1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0430624-A1 | Gear oils and additives therefor | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-05 | — | — | EP | disclosed |