Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.62 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.59 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GCLC | P48506 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864542 | 0.87 | GRM3 (0.69) | FOLH1GRM3NAALAD2CYP1A2GCLC | |
| SCHEMBL5053371 | 0.87 | GRM3 (0.79) | FOLH1GRM3NAALAD2CYP1A2 | |
| SCHEMBL7608702 | 0.81 | FOLH1 (0.72) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8048478 | 0.80 | FOLH1 (0.66) | FOLH1GRM3NAALAD2 | |
| SCHEMBL6037851 | 0.78 | FOLH1 (0.72) | FOLH1GRM3NAALAD2 | |
| SCHEMBL20529841 | 0.78 | GRM3 (0.81) | FOLH1GRM3NAALAD2 | |
| SCHEMBL5051325 | 0.78 | GRM3 (0.81) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7609960 | 0.77 | FOLH1 (0.62) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8060048 | 0.77 | FOLH1 (1.00) | FOLH1GRM3NAALAD2 | |
| SCHEMBL1377526 | 0.77 | GRM3 (0.73) | FOLH1GRM3NAALAD2GCLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999033847-A1 | PHOSPHINIC ALKANOIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1999-07-08 | — | — | WO | claimed |
| WO-1999033847-A9 | PHOSPHINIC ALKANOIC ACID DERIVATIVES | GUILFORD PHARM INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999033847-A1 | PHOSPHINIC ALKANOIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1999-07-08 | — | — | WO | disclosed |