SCHEMBL8469772

SCHEMBL8469772

CC1CCN(NC(=O)C2=NN(c3ccc(Cl)cc3Cl)C(c3ccc(Br)s3)C2)CC1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 16/20 0.56
CNR2 P34972 15/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4606543 0.90 CNR1 (0.59) CNR1CNR2
SCHEMBL8451745 0.89 CNR1 (0.57) CNR1CNR2
SCHEMBL8463173 0.86 CNR1 (0.54) CNR1CNR2
SCHEMBL8473316 0.85 CNR1 (0.54) CNR1CNR2
SCHEMBL4605643 0.85 CNR1 (0.48) CNR1CNR2
SCHEMBL4607381 0.82 CNR1 (0.60) CNR1CNR2
SCHEMBL4606627 0.82 CNR1 (0.62) CNR1CNR2
SCHEMBL4606992 0.82 CNR1 (0.45) CNR1CNR2
SCHEMBL14621182 0.81 CNR1 (0.49) CNR1CNR2
SCHEMBL4606276 0.81 CNR1 (0.46) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1946777-A1 Substituted pyrazoline for preventing weight gain Laboratorios del Dr. Esteve S.A. (ES) 2008-07-23 EP disclosed
EP-1946778-A1 Active substance combination for the treatment of diabetes Laboratorios del Dr. Esteve S.A. (ES) 2008-07-23 EP disclosed
EP-1743894-A1 Heterocyclyl-substituted pyrazoline compounds, their preparation and use as medicaments LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-01-17 EP disclosed