Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408101 | 0.93 | IDO1 (0.73) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16382293 | 0.93 | IDO1 (0.73) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28493083 | 0.85 | IDO1 (0.63) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28484926 | 0.85 | IDO1 (0.63) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28287055 | 0.83 | IDO1 (0.66) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL870689 | 0.79 | CYP3A4 (0.63) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5536059 | 0.79 | IDO1 (0.61) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1927667 | 0.79 | IDO1 (0.61) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL57158 | 0.79 | IDO1 (1.00) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL872215 | 0.79 | IDO1 (0.61) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |