Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 20/20 | 0.56 |
| ▸ | RARG | P13631 | 19/20 | 0.56 |
| ▸ | RARA | P10276 | 18/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043795 | 0.88 | RARB (0.58) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL18868819 | 0.84 | RARB (0.70) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6240117 | 0.84 | RARB (0.76) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8331191 | 0.81 | RARB (0.48) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL5415175 | 0.80 | RARB (0.48) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL7773469 | 0.80 | RARB (0.63) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL5333106 | 0.79 | RARB (0.50) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL5329012 | 0.75 | RARB (0.42) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL27461634 | 0.74 | RARB (0.58) | RARBRARGRARA | |
| SCHEMBL6240996 | 0.74 | RARB (0.61) | RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |