Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 3-Hydroxybenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | P4HB | P07237 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Hydroxybenzoic Acid SCHEMBL8470184 | 1.00 | CA12 (0.67) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL9153881 | 0.82 | CA12 (1.00) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL29378849 | 0.82 | CA12 (1.00) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL40078 | 0.82 | CA12 (1.00) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL8679140 | 0.82 | CA12 (1.00) | CA12CA1CA2CA6CA9 | |
| Adipic Acid SCHEMBL27888600 | 0.80 | CA12 (0.67) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL8921998 | 0.80 | CA12 (0.95) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL381762 | 0.80 | CA12 (0.95) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL18393380 | 0.80 | CA12 (0.95) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL20815892 | 0.80 | CA12 (0.95) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007748-A1 | POLYMER PURIFICATION PROCESSES | CIBA SPECIALTY CHEMICALS WATER TREAMENTS LIMITED (GB) | 1999-02-18 | — | — | WO | disclosed |