Cyclopropane

Cyclopropane

SCHEMBL8470339

C1CC1.O=NO

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL14645512 1.00
Nitrous Acid SCHEMBL10317865 1.00
Nitrous Acid SCHEMBL29104718 0.95
Cyclohexane SCHEMBL27857024 0.95 CA1 (0.60)
Nitrous Acid SCHEMBL30577922 0.82
Nitrous Acid SCHEMBL18095956 0.82 CA1 (1.00)
Nitrous Acid SCHEMBL2328305 0.82
Nitrous Acid SCHEMBL1057 0.82
Nitrous Acid SCHEMBL20212027 0.82
Nitrous Acid SCHEMBL10526485 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5889031-A CONTROLLING CIRCADIAN RHYTHMS BRISTOL-MYERS SQUIBB COMPNAY (US) 1999-03-30 US disclosed
US-5753709-A N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics BRISTOL-MYERS SQUIBB COMPANY (US) 1998-05-19 US disclosed