Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.70 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9576450 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL9576375 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL9576362 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL9576384 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL16230 | 1.00 | — | — | |
| Acetic Acid SCHEMBL29382876 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL9576469 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL29382650 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL9576440 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL9576377 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869220-A | MIXING AND COMMINUTING A PARTIALLY NEUTRALIZED ACID FUNCTIONAL LATEX POLYMER RESIN WITH PHOTOPOLYMERIZABLE MONOMERS AND PHOTOINITIATORS UNDER CONDITIONS SUFFICIENT TO PRODUCE A STABLE EMULSION. | MACDERMID ACUMEN, INC. (US) | 1999-02-09 | — | — | US | disclosed |