Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | IDE | P14735 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559695 | 0.90 | TAAR1 (0.54) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7023461 | 0.89 | TAAR1 (0.48) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31397702 | 0.88 | TAAR1 (0.45) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL366506 | 0.87 | CA1 (0.42) | TAAR1CA1CA2CA4CA9 | |
| SCHEMBL9559728 | 0.87 | TAAR1 (0.49) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11605380 | 0.87 | TAAR1 (0.49) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9559747 | 0.86 | TAAR1 (0.37) | TAAR1CA1CA2CA4CA9 | |
| SCHEMBL28480031 | 0.84 | TAAR1 (0.42) | TAAR1CA1CA2CA4CA9 | |
| SCHEMBL9533106 | 0.83 | CA1 (0.36) | TAAR1CA1CA2CA4CA9 | |
| SCHEMBL294941 | 0.83 | TAAR1 (0.44) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999061014-A2 | COMPOSITIONS AND METHODS EMPLOYING R(-) FLUOXETINE AND OTHER ACTIVE INGREDIENTS | SEPRACOR INC. (US) | 1999-12-02 | — | — | WO | disclosed |