Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967472 | 0.82 | AOC3 (0.50) | AOC3NPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL30843235 | 0.81 | KDM4E (0.43) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL7851584 | 0.81 | KDM4E (0.42) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL4489374 | 0.81 | KDM4E (0.43) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL31353412 | 0.81 | KDM4E (0.42) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL13485804 | 0.81 | AOC3 (0.46) | AOC3NPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL423788 | 0.80 | AOC3 (0.49) | AOC3NPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL10621687 | 0.80 | HPGD (0.43) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL12071539 | 0.79 | AOC3 (0.47) | AOC3NPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL422232 | 0.79 | AOC3 (0.47) | AOC3NPC1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |
| US-5948817-A | Polycyclic ethyl alkylamide melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998038991-A1 | POLYCYCLIC ETHYL ALKYLAMIDE MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |