SCHEMBL8470730

SCHEMBL8470730

Cc1cc(C(OC#N)c2cc(C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.52
CA2 P00918 3/20 0.52
ALDH1A1 P00352 3/20 0.52
POLB P06746 1/20 0.52
TYR P14679 1/20 0.52
HSPA5 P11021 1/20 0.44
CYP2C9 P11712 7/20 0.42
CYP2C19 P33261 7/20 0.42
HIF1A Q16665 5/20 0.42
HSD17B10 Q99714 4/20 0.39
CYP2D6 P10635 2/20 0.39
CYP1A2 P05177 4/20 0.37
CYP3A4 P08684 4/20 0.37
TSHR P16473 4/20 0.37
MAPT P10636 4/20 0.37
TP53 P04637 3/20 0.37
MEN1 O00255 3/20 0.37
BLM P54132 3/20 0.37
KMT2A Q03164 3/20 0.37
ALOX15 P16050 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4390429 0.83 SMN1; SMN2 (0.59) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL8471806 0.81 HSPA5 (0.49) SMN1; SMN2CA2ALDH1A1HSPA5CYP2C9
SCHEMBL4391912 0.79 SMN1; SMN2 (0.57) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL4388465 0.79 SMN1; SMN2 (0.57) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL8927280 0.76 SMN1; SMN2 (0.53) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL4401172 0.76 SMN1; SMN2 (0.53) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL17438141 0.76 SMN1; SMN2 (0.68) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL14571921 0.75 SMN1; SMN2 (0.52) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL225440 0.74 SMN1; SMN2 (0.65) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL29463589 0.74 SMN1; SMN2 (0.65) SMN1; SMN2CA2ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5906905-A Simulated photographic-quality prints using a transparent substrate containing a wrong reading image and a backing sheet containing an ultraviolet light absorber XEROX CORPORATION (US) 1999-05-25 US disclosed
US-5759734-A Method of generating simulated photographic-quality images on luminescent melt-formed backing substrates XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5759727-A TONER IMAGE ON TRANSPARENT SUBSTRATE; MELT POLYMER BACKING XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5693437-A Simulated photographic-quality prints with a hydrophobic scuff resistant coating which is receptive to certain writing materials XEROX CORPORATION (US) 1997-12-02 US disclosed
US-5665504-A Simulated photographic-quality prints using a plasticizer to reduce curl XEROX CORPORATION (US) 1997-09-09 US disclosed
US-5665505-A Simulated photographic-quality prints using a transparent substrate containing a wrong reading image and a backing sheet containing a right reading image of different information XEROX CORPORATION (US) 1997-09-09 US disclosed
US-5663023-A Simulated photographic-quality prints using a transparent substrate containing a wrong reading image and a backing sheet containing a right reading image of the same information XEROX CORPORATION (US) 1997-09-02 US disclosed
US-5612777-A DEVELOPER HOUSING OF WEAR RESISTANT POLYMER AND ULTRAVIOLET RADIATION ABSORBER XEROX CORPORATION (US) 1997-03-18 US disclosed