Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475275 | 0.78 | HSP90AA1 (0.33) | HSP90AA1CDK5CDK5R1 | |
| SCHEMBL8487264 | 0.74 | CDK5 (0.36) | HSP90AA1GRM5CDK5CDK5R1CCNA2 | |
| SCHEMBL8487263 | 0.74 | CDK5 (0.36) | HSP90AA1GRM5CDK5CDK5R1CCNA2 | |
| SCHEMBL8369812 | 0.69 | DRD1 (0.33) | TSHRCASP1 | |
| SCHEMBL6234455 | 0.62 | CDK5 (0.46) | GRM5CDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL13865788 | 0.58 | CDK5 (0.51) | HSP90AA1GRM5CDK5CDK5R1CCNA2 | |
| SCHEMBL9954250 | 0.58 | CDK5 (0.46) | GRM5CDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL426656 | 0.58 | GRM5 (0.51) | GRM5CDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL29564444 | 0.58 | CDK5 (0.46) | GRM5CDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL30676854 | 0.58 | GRM5 (0.51) | GRM5CDK5CDK5R1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925653-A | INSECTICIDES, ACARICIDES AND FUNGICIDES FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES IN THE FIELD OF VETERINARY MEDICINE | HOECHST SCHERING AGREVO GMBH (DE) | 1999-07-20 | — | — | US | disclosed |